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DMT-2'-O-Me-I-CE Phosphoramidite Amount/Package:0.25g / 30mL screwed bottle-28DMT 2' O Me I CE Phosphoramidite is a 2' OMe phosphoramidite monomer used for solid phase oligonucleotide synthesis. It contains a 5' dimethoxytrityl (DMT) protecting group for 5' hydroxyl protection, a hypoxanthine, a cyanoethyl (CE) protecting group on cytosine, and a 2' O methyl (2' OMe) ribose modification The 2' OMe modification improves duplex stability, reduces immunogenicity, and significantly increases resistance to nucleases Applications
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1 (2003): 27-38
"siRNA function in RNAi: a chemical modification analysis
" Pain 109
Mixed backbone design
Purinergic signaling studies involving UTP-responsive P2Y receptors
Flexible deprotection schemes
" Nucleic acids research 23
and Marvin H
David Cowley
in situ hybridization
compatible with TEA·3HF
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