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catalytically active form of interleukin-1 receptor-associated kinase 4 that forms within minutes of TLR/IL-1R stimulation
The protease domain has a conserved structure unique to trypsin-like proteases
with C-terminal 8* His LPKAVVKLDPPWIQVLKEDMVTLMCEGTHNPGNSSTQWFHNGRSVRSQVQASYTFKATVNDSGEYRCQMEQTRLSDPVDLGVISDWLLLQTPQRVFLEGETITLRCHSWRNKLLNRISFFHNEKSVRYHHYKSNFSIPKANHSHSGDYYCKGSLGSTQHQSKPVTITVQDPATTSSISLVWYHTGGGSGGGSHHHHHHHH
It forms an α/β heterodimer with CD18 (integrin β2) to create the Mac-1 complex
SS18-SSX Recombinant Rabbit mAb, PBS Only (SDT-4202) RNA Immunoprecipitation catalytically active form of interleukin-1Product Specification Host Rabbit Antigen SS18 SSX Synonyms SYT SSX1; SS18 SSX1 fusion; SSX1 SSXT fusion Location Nucleus Accession A4PIV8 Clone Number SDT 4202 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt reconstitution, 4C as supplied Dilution
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